dults 18–80 years

Physician-diagnosed mild to moderate asthma for ≥12 months (per GINA)

Daily asthma maintenance therapy for ≥1 month prior, including:
o ICS <500 μg/day fluticasone propionate or
o ICS <800 μg/day budesonide or equivalent
o With or without LABA

≥1 asthma exacerbation in the past year, with at least one occurring while on low-dose ICS (as above)

FeNO ≥50 ppb at screening AND ≥20 ppb at baseline

Blood eosinophils ≥300 cells/μL at screening

BMI 18.5–40 kg/m²

All sexes eligible; effective contraception required